Principal Scientist Job

Company Name:
Malvern, PA, US
Johnson & Johnson companies are equal opportunity employers.
Principal Scientist-00000PY4
Janssen Pharmaceuticals, Inc., a member of Johnson & Johnson's Family of Companies, is currently recruiting for a Principal Scientist. This position will be located in Malvern, PA, Cork, Ireland or Leiden, Netherlands.
Janssen Pharmaceuticals, Inc., a pharmaceutical company of Johnson & Johnson, provides medicines for an array of health concerns in several therapeutic areas, including: attention deficit hyperactivity disorder (ADHD), cardiovascular disease, general medicine (acid reflux disease, infectious diseases), mental health (bipolar I disorder, schizophrenia), neurologics (Alzheimer's disease, epilepsy, migraine prevention and treatment), pain management, and women's health. Our ultimate goal is to help people live healthy lives. We have produced and marketed many first-in-class prescription medications and are poised to serve the broad needs of the healthcare market - from patients to practitioners, from clinics to hospitals. For more about Janssen Pharmaceuticals, Inc., one of the Pharmaceutical Companies of Johnson & Johnson, visit
Responsibilities of this role include: Lead the coordination of technical services activities across the large molecule platform. In this role the incumbent is charged with managing New Product Introduction and Life-Cycle Management projects that must drive reliability and sustainability of our Parenteral bulk drug substance manufacturing plants and products. This person will provide the overall project portfolio management and leadership role to lead and facilitate the activities related to all technical support related to establishing standardized Design-to-Value strategies in the Janssen's Biologics Drug Substance Supply Chain network, for both internal and external manufacturing facilities. This role will partner with R&D, Quality, and Regulatory to ensure processes are flawlessly introduced into and managed through the supply chain network and that models are developed and utilized to ensure both new and ongoing production consistently satisfies quality and regulatory needs. The incumbent must be able to work independently to drive and execute projects of a complex nature where analysis of situations or data requires an in depth evaluation of various identifiable factors in multifunctional areas, and must have strong communication skills to influence other functions/levels outside of own group and effectively leads cross functional and cross organizational teams to generally attain expected results for all parties.
Additional responsibilities include: Establish and implement a strategy for standard manufacturing practice under Design-to-Value guiding principle for new product introduction and marketed product support across large molecule product portfolio in Janssen Supply Chain. Responsible to assure ensure manufacturing reliability and sustainability. Accountable technical lead for identifying new technology or areas of improvements on current and future processes, capital utilization, cost of goods optimization, and advanced expertise on feasibility and risks management. Strengthen external network of academic, regulatory, professional and cross company alliance s to enhance standardization of current approaches and introduction of new technologies across platforms and industry.
Master's of Science degree or equivalent in a technical field (Life Science, Bio Engineering, Chemistry, Pharmaceutics, Chemical Engineering) with a minimum of 8 years experience in the drug substance biopharmaceutical development or manufacturing arena OR Ph.D. with a minimum of 6 years experience in the drug substance biopharmaceutical development or manufacturing arena required; Proven track record in large molecule process development, new product introduction and ongoing production support of large molecule pharmaceutical products required; Experience having accountability and success for design, start-up, and approval of both facilities and products within the large molecule space required; Well established industrial, academic and regulatory track record required; Strong knowledge in biologics bulk drug substance manufacturing processes required; Knowledge of filing strategies and regulatory requirements highly preferred; Hands-on experience in both R&D and Manufacturing Operation is highly preferred; Demonstrated leadership in providing integration of activities, information across multifunctional groups and sites required; Planning and logistics skills capable of effective integration of drug substance deliverables at the manufacturing site level required; Ability to foster team productivity and cohesiveness and to work collaboratively to execute, deliver and get results through the team required; Ability to influence peers, superiors, and external partners required; Excellent written and oral communication skills in English required; International travel up to 30% is required.
Primary Location:
North America-United States-Pennsylvania-Malvern
Other Locations:
Europe/Middle East/Africa-Ireland-Cork-Cork, Europe/Middle East/Africa-Netherlands-South Holland-Leiden
Job Function:
Eligible Yes - Within Country
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